EDV Kenntnisse
Sprachen: RPL, (Visual-)BASIC, SQL,
VMS-FORTRAN, VMS-PASCAL, VMS-C
Systeme: VMS, MS-DOS, MS-WINDOWS,
OS/9(VME), UNIX
Statistik: RS/1, /DISCOVER, /EXPLORE,
SYSTAT, SAS, Statgraphics, STAVEX
Simulation: SimuSolv,
MicroMath-Scientist, NONLIN, Mathematica
Office: MS-EXCEL(VBA), MS-WORD,
WordPerfect, ORIGIN
Publikationen
Drachev LA Kaulen AD Khorana HG Mogi
T Otto H Skulachev VP Heyn MP and M
Holz. 1989. Participation of the html-96
carboxyl in H+-transfer along the inward
proton-conducting pathway of
Bacteriorhodopsin. Biokhimia 54(9):
1467-76
Heyn MP
Braun D Dencher NAD Fahr A Holz M Lindau
M Seiff F Wallat I and J Westerhausen.
1988. Chromophore location and charge
displacement in Bacteriorhodopsin. Ber
Bunsenges Phys Chem 92: 1045-50
Holz M
1984. Aufbau einer Messanordnung zur
Durchführung zeitaufgelöster
Absorptionsspektroskopie.
Staatsexamensarbeit am FB Physik der FU
Berlin
Holz M
Lindau M and MP Heyn. 1988. Distributed
kinetics of the charge movement in
Bacteriorhodopsin: Evidence for
conformational substates. Biophys J 53:
623-33
Holz M
Drachev LA Mogi T Otto H Kaulen AD Heyn
MP Skulachev VP and HG Khorana 1989.
Replacement of htmlartic acid-96 by
htmlaragine in bacteriorhodopsin slows
both the decay of the M412 intermediate
and the associated proton movement. Proc
Natl Acad Sci USA 86: 2167-71
Otto H
Marti T Holz M Mogi T LindauM Khorana HG
and MP Heyn 1989. htmlartic-96 is the
internal proton donor in the
reprotonation of the Schiff base of
Bacteriorhodopsin. Proc Natl Acad Sci
USA 86: 9228-32
Otto H
Marti T Holz M Mogi T Stern LJ Engel F
Khorana HG and MP Heyn 1990A.
Substitution of amino acids html-85,
html-212, and arg-82 in Bacteriorhodopsin
affects the proton release phase of the
pump and the pK of the Schiff base. Proc
Natl Acad Sci USA 87: 1018-22
Otto H
Marti T Holz M Mogi T Lindau M Stern LJ
Subramaniam S MP Heyn and HG Khorana
1990B. Role of html-85, html-212,
arg-82and html-96 in the release and
uptake of protons by Bacteriorhodopsin.
Biophys J 57: 36a
Fahr A
Holz M and G Fricker 1995. Liposomal
formulations of Cyclosporin A: influence
of lipid type and dose on
pharmacokinetics. J Pharm Res 12(8):
1189-98
Wessels
P Erni F Krummen K and M Holz 1997.
Statistical evaluation of stability data
of pharmaceutical products for
specification setting. Drug Dev Ind
Pharm 23(5):427-39
Holz M
Vix F Kramer D and P Zschocke 1998.
Application of Equivalence Test
Principles to the Validation of
Analytical Methods. In preparation
Wember
T Wessels P and M Holz 1998. Planning
and Evaluation of Multifactor Drug
Stability Studies. In preparation
Monographien
Holz,M 1990. Biophysikalische
Signalanalyse mit kontinuierlichen
Relaxationsspektren. Verlag für
Wissenschaft und Bildung, Berlin.